close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1777Conserved hypothetical protein; Similar to GB:L42023 PID:1003114 PID:1222018 PID:1204364 SP:Q57354 percent identity: 34.16; identified by sequence similarity; putative. (245 aa)    
Predicted Functional Partners:
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.719
AF_0324
dTDP-glucose 4,6-dehydratase (rfbB); Similar to PID:567874 percent identity: 50.00; identified by sequence similarity; putative.
  
    0.708
AF_1784
Protoporphyrinogen oxidase (hemK); Putative protein methyltransferase using S-adenosyl-L- methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity); Belongs to the eukaryotic/archaeal PrmC-related family.
  
    0.669
spoVG
Stage V sporulation protein (spoVG); Could be involved in septation.
 
     0.603
AF_1781
Nodulation protein NfeD (nfeD); Similar to PID:1145796 percent identity: 33.41; identified by sequence similarity; putative.
       0.592
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
  
  
 0.547
AF_1780
Acetolactate synthase, large subunit (ilvB-2); Similar to GB:L77117 SP:Q57725 PID:1591003 percent identity: 32.06; identified by sequence similarity; putative; Belongs to the TPP enzyme family.
 
    0.531
AF_1062
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57905 PID:1591185 percent identity: 57.76; identified by sequence similarity; putative.
 
   
 0.528
hisC1
Histidinol-phosphate aminotransferase (hisC-1); Similar to GB:L77117 PID:1591622 percent identity: 39.76; identified by sequence similarity; putative.
  
  
 0.503
hisC2
Histidinol-phosphate aminotransferase (hisC-2); Similar to GB:L77117 PID:1591622 percent identity: 36.83; identified by sequence similarity; putative.
  
  
 0.503
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.