Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1785Iron-dependent repressor; Similar to GB:L77117 SP:Q57988 PID:1592296 percent identity: 41.96; identified by sequence similarity; putative. (191 aa)    
Predicted Functional Partners:
AF_1786
Conserved hypothetical protein; Similar to PID:1001492 PID:1001553 percent identity: 34.09; identified by sequence similarity; putative.
       0.610
AF_1787
Conserved hypothetical protein; Similar to GB:L77117 PID:1591790 percent identity: 34.42; identified by sequence similarity; putative.
       0.610
polB
Conserved hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity); Belongs to the DNA polymerase delta/II small subunit family.
 
     0.594
AF_1791
Signal sequence peptidase (sec11); Similar to GB:Z47047 SP:P15367 PID:4433 PID:557828 PID:763367 percent identity: 36.30; identified by sequence similarity; putative.
  
    0.568
AF_1984
Iron-dependent repressor (troR); Similar to GP:1777937 percent identity: 28.35; identified by sequence similarity; putative.
 
   
 0.539
AF_1788
Methylthioadenosine phosphorylase (mtaP); Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
       0.534
AF_1789
Xanthine-guanine phosphoribosyltransferase (gptA-2); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 28.16; identified by sequence similarity; putative.
       0.531
AF_1982
ABC transporter, ATP-binding protein; Similar to GP:1777934 percent identity: 41.30; identified by sequence similarity; putative.
 
  
 0.510
AF_1983
ABC transporter, periplasmic binding protein; Similar to GP:1777933 percent identity: 25.39; identified by sequence similarity; putative.
 
  
 0.508
AF_1843
Cobalamin biosynthesis protein (cbiM-2); May be involved in nickel transport; Belongs to the CbiM family. NikM subfamily.
     
 0.477
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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