STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AF_1788Methylthioadenosine phosphorylase (mtaP); Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. (243 aa)    
Predicted Functional Partners:
AF_0370
Translation initiation factor eIF-2B, subunit delta (eif2BD); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
 
 
 0.974
mtaD1
N-ethylammeline chlorohydrolase (trzA-1); Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
 
 0.964
mtaD2
N-ethylammeline chlorohydrolase (trzA-2); Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
 
 0.955
speE
Spermidine synthase (speE); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
 
 0.954
AF_1789
Xanthine-guanine phosphoribosyltransferase (gptA-2); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 28.16; identified by sequence similarity; putative.
  
  
 0.868
polB
Conserved hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity); Belongs to the DNA polymerase delta/II small subunit family.
       0.773
guaAB
GMP synthase (guaA-1); Catalyzes the synthesis of GMP from XMP.
 
 
 0.725
AF_1786
Conserved hypothetical protein; Similar to PID:1001492 PID:1001553 percent identity: 34.09; identified by sequence similarity; putative.
       0.700
AF_0480
Fuculose-1-phosphate aldolase (fucA); Similar to GB:L77117 SP:Q58813 PID:1592067 percent identity: 31.84; identified by sequence similarity; putative.
  
  
 0.689
AF_1787
Conserved hypothetical protein; Similar to GB:L77117 PID:1591790 percent identity: 34.42; identified by sequence similarity; putative.
       0.668
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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