Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1793Repressor protein; Similar to GB:L77117 PID:1590997 percent identity: 54.55; identified by sequence similarity; putative. (70 aa)    
Predicted Functional Partners:
AF_1792
Predicted coding region AF_1792; Hypothetical protein; identified by GeneMark; putative.
  
    0.739
AF_1791
Signal sequence peptidase (sec11); Similar to GB:Z47047 SP:P15367 PID:4433 PID:557828 PID:763367 percent identity: 36.30; identified by sequence similarity; putative.
       0.588
AF_1747
Nitrogen regulatory protein P-II (glnB-2); Similar to GB:L77117 SP:Q60381 PID:1592259 percent identity: 58.04; identified by sequence similarity; putative; Belongs to the P(II) protein family.
     
 0.462
AF_0077
Aldehyde ferredoxin oxidoreductase (aor-2); Similar to PID:736274 percent identity: 32.65; identified by sequence similarity; putative.
      
 0.453
AF_2281
Aldehyde ferredoxin oxidoreductase (aor-4); Similar to PID:736274 percent identity: 52.97; identified by sequence similarity; putative.
      
 0.453
AF_1788
Methylthioadenosine phosphorylase (mtaP); Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
       0.442
AF_1789
Xanthine-guanine phosphoribosyltransferase (gptA-2); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 28.16; identified by sequence similarity; putative.
       0.442
polB
Conserved hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity); Belongs to the DNA polymerase delta/II small subunit family.
       0.442
glnA
Glutamine synthetase (glnA); Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Beta-glutamate is a much poorer substrate than alpha-glutamate; Belongs to the glutamine synthetase family.
     
 0.429
ftsZ2
Cell division protein (ftsZ-2); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.427
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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