Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AF_1796Conserved hypothetical protein; Similar to SP:P42404 PID:710636 PID:1438846 PID:1805417 GB:AL009126 percent identity: 36.61; identified by sequence similarity; putative; Belongs to the SIS family. PHI subfamily. (183 aa)    
Predicted Functional Partners:
AF_0861
D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hps-1); Similar to GB:L77117 SP:Q58842 PID:1592092 percent identity: 30.59; identified by sequence similarity; putative.
 
 0.998
fae-hps
D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hps-2); Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
 
 0.997
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.954
AF_1494
Predicted coding region AF_1494; Hypothetical protein; identified by GeneMark; putative.
  
 
  0.930
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
 0.912
AF_1795
Endoglucanase (celM); Similar to GB:L77117 SP:Q57975 PID:1591260 percent identity: 55.37; identified by sequence similarity; putative.
       0.799
AF_1797
Phosphate regulatory protein, putative; Similar to PID:633996 percent identity: 30.67; identified by sequence similarity; putative.
     
 0.639
AF_1182
Predicted coding region AF_1182; Hypothetical protein; identified by GeneMark; putative.
       0.619
AF_1181
GTP-binding protein; Similar to GP:1732241 percent identity: 36.26; identified by sequence similarity; putative.
       0.617
rpiA
Ribose 5-phosphate isomerase (rpi); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
  
 0.594
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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