Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1801Conserved hypothetical protein; Similar to GB:L77117 PID:1592115 percent identity: 35.16; identified by sequence similarity; putative. (226 aa)    
Predicted Functional Partners:
AF_1800
Conserved hypothetical protein; Similar to GB:L77117 PID:1591804 percent identity: 26.77; identified by sequence similarity; putative.
       0.788
AF_1989
Peptidyl-prolyl cis-trans isomerase (slyD); Similar to GB:L77117 SP:Q58235 PID:1591512 percent identity: 34.38; identified by sequence similarity; putative.
 
     0.709
ef1b
Translation elongation factor EF-1, subunit beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
 
   
 0.685
AF_1695
Thiamine biosynthesis protein (apbA); Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
       0.624
AF_2149
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58046 PID:1591340 percent identity: 30.14; identified by sequence similarity; putative; Belongs to the UPF0111 family.
       0.624
ogt
methylated-DNA-protein-cysteine methyltransferase (ogt); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.624
AF_2369
Predicted coding region AF_2369; Hypothetical protein; identified by GeneMark; putative.
       0.624
rlmE
Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
  
   
 0.607
AF_0477
AAA superfamily ATPase; Similar to GB:D78275 SP:Q92524 PID:1526426 PID:2213932 percent identity: 34.97; identified by sequence similarity; putative; Belongs to the AAA ATPase family.
       0.593
AF_0478
ATP-binding protein PhnP (phnP); Similar to GB:D90227 SP:P16692 PID:147213 PID:216605 PID:536936 percent identity: 30.94; identified by sequence similarity; putative.
       0.593
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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