Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1884Daunorubicin resistance ATP-binding protein (drrA); Similar to GP:1707742 percent identity: 47.06; identified by sequence similarity; putative. (398 aa)    
Predicted Functional Partners:
AF_1883
Daunorubicin resistance membrane protein (drrB); Similar to GB:M73758 SP:P32011 GB:L37338 PID:153231 percent identity: 27.04; identified by sequence similarity; putative.
 
  
 0.961
AF_1005
ABC transporter, ATP-binding protein, putative; Similar to SP:P37624 PID:912462 PID:2367231 percent identity: 26.69; identified by sequence similarity; putative.
  
 0.959
AF_1471
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58119 PID:1591425 percent identity: 38.96; identified by sequence similarity; putative.
  
  
 0.724
AF_0824
Branched-chain amino acid ABC transporter, permease protein (braE-2); Similar to SP:P22729 GB:U00039 PID:466592 GB:U00096 PID:1789865 percent identity: 31.33; identified by sequence similarity; putative.
      0.713
AF_1137
Predicted coding region AF_1137; Hypothetical protein; identified by GeneMark; putative.
  
 
 0.672
fusA
Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...]
 
  
 0.611
AF_0225
Branched-chain amino acid ABC transporter, permease protein (braE-1); Similar to PID:146634 percent identity: 28.72; identified by sequence similarity; putative.
      0.594
rpoH
DNA-directed RNA polymerase, subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
       0.572
AF_1886
DNA-directed RNA polymerase, subunit B'' (rpoB2); Similar to SP:P15352 PID:43540 percent identity: 57.14; identified by sequence similarity; putative; Belongs to the RNA polymerase beta chain family.
     
 0.536
rpoB1
DNA-directed RNA polymerase, subunit B' (rpoB1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.
     
 0.536
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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