Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AF_1901Conserved hypothetical transmembrane protein; Similar to GB:L77117 SP:Q57904 PID:1591183 percent identity: 27.49; identified by sequence similarity; putative. (221 aa)    
Predicted Functional Partners:
secY
Protein translocase, subunit SEC61 alpha (secY); The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
 
    0.951
rps5
SSU ribosomal protein S5P (rps5P); With S4 and S12 plays an important role in translational accuracy.
 
    0.937
rpl15
LSU ribosomal protein L15P (rpl15P); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
    0.935
rps3
SSU ribosomal protein S3P (rps3P); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
    0.933
rpl32e
LSU ribosomal protein L32E (rpl32E); Similar to GB:L77117 SP:P54010 PID:1591174 percent identity: 51.22; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL32 family.
 
    0.929
rpl19e
LSU ribosomal protein L19E (rpl19E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
 
    0.923
rpl30
LSU ribosomal protein L30P (rpl30P); Similar to GB:L77117 SP:P54046 PID:1591178 percent identity: 55.92; identified by sequence similarity; putative.
 
    0.920
cmk
Cytidylate kinase (cmk); Similar to GB:L77117 SP:Q58071 PID:1591369 percent identity: 48.59; identified by sequence similarity; putative.
 
     0.919
rpl18
LSU ribosomal protein L18P (rpl18P); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
     0.907
rpl3
LSU ribosomal protein L3P (rpl3P); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
    0.907
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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