Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1927Conserved hypothetical protein; Similar to GB:L77117 SP:Q58100 PID:1592301 percent identity: 27.27; identified by sequence similarity; putative. (206 aa)    
Predicted Functional Partners:
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
       0.653
AF_1018
ABC transporter, ATP-binding protein; Similar to GB:L77117 SP:Q58206 PID:1591493 percent identity: 57.71; identified by sequence similarity; putative.
   
 
 0.638
AF_1469
ABC transporter, ATP-binding protein; Similar to GB:L77117 SP:Q58206 PID:1591493 percent identity: 59.46; identified by sequence similarity; putative.
   
 
 0.638
AF_1819
ABC transporter, ATP-binding protein; Similar to GB:L77117 SP:Q58206 PID:1591493 percent identity: 51.13; identified by sequence similarity; putative.
   
 
 0.638
rpl4
LSU ribosomal protein L4P (rpl4P); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
       0.632
rps3
SSU ribosomal protein S3P (rps3P); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
     
 0.621
rpl14
LSU ribosomal protein L14P (rpl14P); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
    0.607
rpl30
LSU ribosomal protein L30P (rpl30P); Similar to GB:L77117 SP:P54046 PID:1591178 percent identity: 55.92; identified by sequence similarity; putative.
  
    0.602
rps17
SSU ribosomal protein S17P (rps17P); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
    0.601
rpl23
LSU ribosomal protein L23P (rpl23P); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
       0.601
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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