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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1937Cell division inhibitor (minD-2); Similar to GB:L77117 SP:Q57967 PID:1591252 percent identity: 32.75; identified by sequence similarity; putative. (252 aa)    
Predicted Functional Partners:
AF_1936
Conserved hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.733
cheB
Protein-glutamate methylesterase (cheB); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
  
 0.606
AF_1938
Conserved hypothetical protein; Catalyzes the reversible conversion of a variety of acids to the corresponding acyl-CoA esters. Shows the highest activity with the aryl acids, indoleacetate and phenylacetate, as compared to acetate. In the reverse direction, phenylacetyl-CoA is the best substrate. Seems to be involved primarily in the degradation of aryl-CoA esters to the corresponding acids. Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters. In the C-terminal section; belongs to the acetate CoA ligase alpha subunit family.
       0.540
mch
N5,N10-methenyltetrahydromethanopterin cyclohydrolase (mch); Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
       0.535
AF_1044
Purine-binding chemotaxis protein (cheW); Similar to GB:M26411 SP:P21821 PID:148348 percent identity: 40.41; identified by sequence similarity; putative.
 
  
 0.515
cheD
Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
  
  
 0.500
AF_0697
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57966 PID:1591251 percent identity: 38.46; identified by sequence similarity; putative.
  
    0.445
AF_0996
Type II secretion system protein (gspE-3); Similar to GB:L77117 SP:Q58310 PID:1591575 percent identity: 41.71; identified by sequence similarity; putative.
 
  
 0.421
AF_0338
Type II secretion system protein (gspE-1); Similar to GB:L77117 SP:Q58310 PID:1591575 percent identity: 38.51; identified by sequence similarity; putative.
 
  
 0.419
AF_0659
Type II secretion system protein (gspE-2); Similar to GB:L77117 SP:Q58310 PID:1591575 percent identity: 38.17; identified by sequence similarity; putative.
 
  
 0.412
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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