Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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purLPhosphoribosylformylglycinamidine synthase II (purL); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (765 aa)    
Predicted Functional Partners:
purF
Amidophosphoribosyltransferase (purF); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
 0.999
purD
Phosphoribosylamine--glycine ligase (purD); Similar to GB:L42023 SP:P43845 PID:1005977 PID:1220991 PID:1205135 percent identity: 40.90; identified by sequence similarity; putative.
  
 0.999
purQ
Phosphoribosylformylglycinamidine synthase I (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to a [...]
 0.999
purE
Phosphoribosylaminoimidazole carboxylase (purE); Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 
 0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase (purM); Similar to GB:L77117 SP:Q57656 PID:1590946 percent identity: 53.77; identified by sequence similarity; putative.
 
 
 0.999
purS
Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer [...]
 
 0.999
purB
Adenylosuccinate lyase (purB); Similar to GB:L77117 PID:1591600 percent identity: 52.27; identified by sequence similarity; putative.
 
  
 0.992
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase (purC); Similar to GB:L77117 PID:1592203 percent identity: 34.71; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. Highly divergent.
 
 
 0.979
AF_1811
Inosine monophosphate cyclohydrolase; Similar to SP:P15639 GB:J05126 GB:X51950 PID:147420 PID:396345 percent identity: 38.27; identified by sequence similarity; putative.
 
  
 0.976
guaAB
GMP synthase (guaA-1); Catalyzes the synthesis of GMP from XMP.
  
  
 0.969
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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