STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
albA2Conserved hypothetical protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. (89 aa)    
Predicted Functional Partners:
dnaG
Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.666
AF_1531
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60345 PID:1498798 percent identity: 43.68; identified by sequence similarity; putative.
  
     0.632
AF_1957
2-hydroxyglutaryl-CoA dehydratase, subunit beta (hgdB); Similar to GB:X14252 SP:P11570 PID:38802 percent identity: 24.40; identified by sequence similarity; putative.
       0.623
AF_1958
2-hydroxyglutaryl-CoA dehydratase, subunit alpha (hgdA); Similar to GB:X14252 SP:P11569 PID:38800 percent identity: 30.54; identified by sequence similarity; putative.
       0.623
AF_1959
(R)-hydroxyglutaryl-CoA dehydratase activator (hgdC); Similar to SP:P11568 GB:X59645 PID:433932 percent identity: 51.21; identified by sequence similarity; putative.
       0.623
nep1
Conserved hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
 
   
 0.613
pheS
phenylalanyl-tRNA synthetase, subunit alpha (pheS); Similar to GB:L77117 SP:Q57911 PID:1592293 percent identity: 44.39; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
       0.566
AF_1251
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57570 PID:1590883 percent identity: 38.16; identified by sequence similarity; putative.
  
    0.544
csl4
Predicted coding region AF_0206; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs (Probable).
  
   
 0.524
eif2b
Translation initiation factor eIF-2, subunit beta, putative; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family.
 
   
 0.523
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.