Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1960DNA helicase, putative; Similar to GB:L77117 SP:Q57568 PID:1590880 percent identity: 32.71; identified by sequence similarity; putative. (453 aa)    
Predicted Functional Partners:
AF_2350
ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative.
 
 
 0.818
AF_0539
Conserved hypothetical protein; Similar to PID:662338 percent identity: 34.10; identified by sequence similarity; putative.
   
 0.787
AF_1181
GTP-binding protein; Similar to GP:1732241 percent identity: 36.26; identified by sequence similarity; putative.
   
 0.787
AF_2209
Conserved hypothetical protein; Similar to SP:P46577 percent identity: 31.33; identified by sequence similarity; putative.
   
 0.787
AF_0532
mRNA 3'-end processing factor, putative; Similar to GB:L77117 SP:Q60355 PID:1590845 percent identity: 39.36; identified by sequence similarity; putative.
   
 0.781
AF_2361
mRNA 3'-end processing factor, putative; Similar to GP:1707412 percent identity: 30.49; identified by sequence similarity; putative.
   
 0.781
eif2a
Translation initiation factor eIF-2, subunit alpha (eif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
   
 
 0.693
radA
DNA repair protein RAD51 (radA); Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
 
 
 
 0.649
rpl3
LSU ribosomal protein L3P (rpl3P); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
  0.632
AF_0865
Carboxylesterase (est-1); Similar to GB:D14529 PID:402521 percent identity: 27.06; identified by sequence similarity; putative.
   
 0.617
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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