Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AF_1968Transcriptional regulatory protein, Rok family; Similar to PID:1208894 SP:Q44406 percent identity: 32.91; identified by sequence similarity; putative. (254 aa)    
Predicted Functional Partners:
AF_2037
Translation initiation factor eIF-2B, subunit delta (eif2BD); Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
       0.618
AF_0401
Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative.
 
  
 0.611
AF_0356
Carbohydrate kinase, pfkB family; Similar to SP:P36945 GB:Z25798 PID:397495 PID:1894761 GB:AL009126 percent identity: 31.28; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.606
pgk
3-phosphoglycerate kinase (pgk); Similar to GB:L77117 SP:Q58058 PID:1592299 percent identity: 48.77; identified by sequence similarity; putative.
 
   
 0.575
AF_2101
Alcohol dehydrogenase, zinc-dependent; Similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126 percent identity: 30.06; identified by sequence similarity; putative.
 
  
 0.575
AF_1969
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58220 PID:1592310 percent identity: 55.84; identified by sequence similarity; putative.
       0.574
AF_0035
Mannosephosphate isomerase, putative; Similar to GB:D16594 PID:451216 SP:Q59935 percent identity: 31.30; identified by sequence similarity; putative.
  
  
 0.520
gap
Glyceraldehyde 3-phosphate dehydrogenase (gap); Similar to SP:P10618 PID:149792 percent identity: 56.59; identified by sequence similarity; putative.
     
 0.512
AF_0866
Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
 
  
 0.510
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
 0.508
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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