Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1969Conserved hypothetical protein; Similar to GB:L77117 SP:Q58220 PID:1592310 percent identity: 55.84; identified by sequence similarity; putative. (202 aa)    
Predicted Functional Partners:
AF_2310
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57846 PID:1591108 percent identity: 47.01; identified by sequence similarity; putative; Belongs to the MEMO1 family.
    0.992
AF_1330
Pyruvate formate-lyase activating enzyme (act-3); Similar to GB:L77117 SP:Q58218 PID:1499631 percent identity: 45.81; identified by sequence similarity; putative.
     0.971
AF_2278
Pyruvate formate-lyase activating enzyme (act-4); Similar to GB:L77117 SP:Q58218 PID:1499631 percent identity: 42.46; identified by sequence similarity; putative.
     0.887
AF_0117
Pyruvate formate-lyase activating enzyme (act-1); Similar to GB:L77117 PID:1591858 percent identity: 25.47; identified by sequence similarity; putative.
 
     0.648
AF_0571
Conserved hypothetical protein; Similar to PID:1226043 percent identity: 36.00; identified by sequence similarity; putative.
  
    0.639
AF_2058
Conserved hypothetical protein; Similar to GB:L77117 PID:1499875 percent identity: 31.73; identified by sequence similarity; putative.
       0.624
pyrC
Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
       0.624
pgk
3-phosphoglycerate kinase (pgk); Similar to GB:L77117 SP:Q58058 PID:1592299 percent identity: 48.77; identified by sequence similarity; putative.
       0.616
AF_0655
Conserved hypothetical protein; Probable metalloprotease.
       0.587
AF_1968
Transcriptional regulatory protein, Rok family; Similar to PID:1208894 SP:Q44406 percent identity: 32.91; identified by sequence similarity; putative.
       0.574
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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