Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cutAPeriplasmic divalent cation tolerance protein (cutA); Involved in resistance toward heavy metals. (102 aa)    
Predicted Functional Partners:
AF_1322
Conserved hypothetical protein; Similar to GB:L77117 PID:1591634 percent identity: 33.23; identified by sequence similarity; putative.
       0.932
AF_1979
Conserved hypothetical protein; Similar to GP:1707808 percent identity: 44.92; identified by sequence similarity; putative.
       0.872
AF_1977
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58006 PID:1591294 percent identity: 38.46; identified by sequence similarity; putative.
  
    0.751
cbiN
Cobalt transport protein (cbiN); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.
      
 0.738
katG
Peroxidase / catalase (perA); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity.
     
 0.611
cbiM
Cobalamin biosynthesis protein (cbiM-1); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
      
 0.536
acyP
Acylphosphatase (acyP); Similar to SP:P14620 percent identity: 36.76; identified by sequence similarity; putative.
       0.516
AF_1433
Conserved hypothetical protein; Similar to GB:L77117 PID:1591781 percent identity: 31.58; identified by sequence similarity; putative; Belongs to the UPF0215 family.
       0.516
AF_0344
Desulfoferrodoxin, putative; Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
  
    0.506
AF_0833
Desulfoferrodoxin (dfx); Similar to GB:M81168 SP:P20418 GB:M28848 PID:145115 PID:758676 percent identity: 63.03; identified by sequence similarity; putative; Belongs to the desulfoferrodoxin family.
  
    0.506
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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