Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1981ABC transporter, permease protein; Similar to GB:L11577 SP:P42361 percent identity: 29.88; identified by sequence similarity; putative. (264 aa)    
Predicted Functional Partners:
AF_1982
ABC transporter, ATP-binding protein; Similar to GP:1777934 percent identity: 41.30; identified by sequence similarity; putative.
 
 
 0.999
AF_1983
ABC transporter, periplasmic binding protein; Similar to GP:1777933 percent identity: 25.39; identified by sequence similarity; putative.
 
  
 0.995
AF_1984
Iron-dependent repressor (troR); Similar to GP:1777937 percent identity: 28.35; identified by sequence similarity; putative.
 
  
 0.965
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
     
 0.823
AF_2232
Ferric uptake regulation protein (fur); Similar to GB:U06072 PID:508861 percent identity: 25.77; identified by sequence similarity; putative; Belongs to the Fur family.
 
  
 0.755
AF_1980
Heme exporter protein C (helC); Similar to SP:P29961 GB:X63462 PID:46026 percent identity: 29.02; identified by sequence similarity; putative.
  
  
 0.702
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
     
 0.682
eIF1A
Translation initiation factor eIF-1A (eif1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
       0.595
AF_0743
Conserved hypothetical protein; Transcriptional regulator.
     
 0.563
rio1
Conserved hypothetical protein; Autophosphorylation of the rio1 protein is not necessary for maintenance of kinase activity. Prefers ATP over GTP. The yeast ortholog is involved in ribosome biogenesis. Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity).
       0.561
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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