STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1983ABC transporter, periplasmic binding protein; Similar to GP:1777933 percent identity: 25.39; identified by sequence similarity; putative. (322 aa)    
Predicted Functional Partners:
AF_1981
ABC transporter, permease protein; Similar to GB:L11577 SP:P42361 percent identity: 29.88; identified by sequence similarity; putative.
 
  
 0.995
AF_1982
ABC transporter, ATP-binding protein; Similar to GP:1777934 percent identity: 41.30; identified by sequence similarity; putative.
 
  
 0.995
AF_1984
Iron-dependent repressor (troR); Similar to GP:1777937 percent identity: 28.35; identified by sequence similarity; putative.
  
  
 0.860
rps14
SSU ribosomal protein S14P (rps14P); Binds 16S rRNA, required for the assembly of 30S particles.
  
  
 0.727
AF_2232
Ferric uptake regulation protein (fur); Similar to GB:U06072 PID:508861 percent identity: 25.77; identified by sequence similarity; putative; Belongs to the Fur family.
 
  
 0.673
AF_1980
Heme exporter protein C (helC); Similar to SP:P29961 GB:X63462 PID:46026 percent identity: 29.02; identified by sequence similarity; putative.
       0.661
ilvC
Ketol-acid reductoisomerase (ilvC); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH or NADH to yield (R)-2,3-dihydroxy-isovalerate. It is able to use both NADPH and NADH, but has a preference for NADH.
     
 0.596
AF_0743
Conserved hypothetical protein; Transcriptional regulator.
       0.516
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
     
 0.511
AF_1766
Amino-acid ABC transporter, periplasmic binding protein/protein kinase; Similar to SP:P54952 PID:1408498 GB:AL009126 percent identity: 27.40; identified by sequence similarity; putative.
  
  
 0.510
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.