STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
moaAMolybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (296 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
AF_2005
Molybdopterin-guanine dinucleotide biosynthesis protein A (mobA); Similar to GB:L77117 PID:1592243 percent identity: 33.16; identified by sequence similarity; putative.
 
  
 0.944
AF_2179
Molybdopterin converting factor, subunit 2 (moaE); Similar to PID:1001216 PID:1001213 percent identity: 33.33; identified by sequence similarity; putative.
 
  
 0.931
AF_0265
Molybdenum cofactor biosynthesis protein (moaB); Similar to GB:L77117 PID:1592270 percent identity: 44.44; identified by sequence similarity; putative.
 
  
 0.918
ribA
GTP cyclohydrolase II (ribA-1); Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; In the N-terminal section; belongs to the DHBP synthase family.
    
  0.903
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
    
  0.900
AF_0930
Molybdenum cofactor biosynthesis protein (moeA-2); Similar to GB:L77117 SP:Q58080 PID:1591380 percent identity: 44.81; identified by sequence similarity; putative.
 
 0.876
AF_0161
Molybdenum cofactor biosynthesis protein (moeA-3); Similar to PID:1001216 PID:1001210 percent identity: 30.50; identified by sequence similarity; putative.
 
 0.864
AF_2007
Riboflavin-specific deaminase (ribG); Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6- ribitylamino-4(3H)-pyrimidinone 5'-phosphate.
     
 0.841
AF_0372
Conserved hypothetical protein; Similar to GB:Z35277 SP:P39756 PID:580895 PID:1648855 GB:AL009126 percent identity: 30.16; identified by sequence similarity; putative.
 
  
 0.837
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.