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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2029Conserved hypothetical protein; Similar to GB:L77117 PID:1592223 percent identity: 39.41; identified by sequence similarity; putative. (473 aa)    
Predicted Functional Partners:
dacZ
Conserved hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
   
 0.719
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
 
   
 0.710
AF_1559
Conserved hypothetical protein; Similar to GB:L77117 PID:1591768 percent identity: 27.88; identified by sequence similarity; putative.
 
    0.702
infB
Translation initiation factor IF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
  
  
 0.699
iorB
Indolepyruvate ferredoxin oxidoreductase, subunit beta (iorB); Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
       0.682
AF_2028
Conserved hypothetical protein; Similar to GB:L77117 PID:1592040 percent identity: 36.13; identified by sequence similarity; putative.
       0.546
alaS
alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Incorrectly charged aminoacyl-tRNA(Ala) is also edited in situ by the editing domain.
  
  
 0.535
AF_0934
Conserved hypothetical protein; Similar to GB:L77117 PID:1500498 percent identity: 31.88; identified by sequence similarity; putative.
 
     0.530
truB
Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
  
 0.519
AF_0615
Predicted coding region AF_0615; Hypothetical protein; identified by GeneMark; putative.
 
     0.519
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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