Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2029Conserved hypothetical protein; Similar to GB:L77117 PID:1592223 percent identity: 39.41; identified by sequence similarity; putative. (473 aa)    
Predicted Functional Partners:
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
 
   
 0.819
dacZ
Conserved hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
 
   
 0.752
iorB
Indolepyruvate ferredoxin oxidoreductase, subunit beta (iorB); Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
       0.670
AF_1559
Conserved hypothetical protein; Similar to GB:L77117 PID:1591768 percent identity: 27.88; identified by sequence similarity; putative.
 
    0.638
infB
Translation initiation factor IF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
  
    0.583
mptE
Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
       0.576
AF_2028
Conserved hypothetical protein; Similar to GB:L77117 PID:1592040 percent identity: 36.13; identified by sequence similarity; putative.
       0.546
AF_0934
Conserved hypothetical protein; Similar to GB:L77117 PID:1500498 percent identity: 31.88; identified by sequence similarity; putative.
 
     0.533
AF_0899
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58527 PID:1499979 percent identity: 45.15; identified by sequence similarity; putative.
  
     0.487
AF_0243
Conserved hypothetical protein; Similar to GB:L77117 PID:1590999 percent identity: 45.88; identified by sequence similarity; putative.
       0.486
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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