Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
asd-2Phosphatidylserine decarboxylase (psd2); Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer). (195 aa)    
Predicted Functional Partners:
AF_2044
CDP-diacylglycerol--serine O-phosphatidyltransferase (pssA); Similar to GB:L77117 SP:Q58609 PID:1591841 percent identity: 36.65; identified by sequence similarity; putative.
 
  
 0.982
AF_2046
Cytochrome oxidase, subunit I, putative; Similar to GP:1773053 percent identity: 25.14; identified by sequence similarity; putative.
    
 0.981
AF_2043
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57851 PID:1591114 percent identity: 31.71; identified by sequence similarity; putative.
       0.809
egsA
Sn-glycerol-1-phosphate dehydrogenase (gldA); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
  
   
 0.782
AF_2047
Thymidylate synthase, putative; Similar to GB:M19653 SP:P00469 PID:149601 percent identity: 33.14; identified by sequence similarity; putative.
  
  
 0.781
mvk
Mevalonate kinase (mvk); Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
      
 0.747
AF_1420
Membrane protein; Similar to GB:L77117 SP:Q58237 PID:1591514 percent identity: 51.83; identified by sequence similarity; putative.
   
 
 0.689
AF_1265
Conserved hypothetical protein; Similar to GB:L77117 PID:1591789 percent identity: 50.00; identified by sequence similarity; putative; Belongs to the UPF0173 family.
   
 
 0.667
AF_2153
Conserved hypothetical protein; Similar to GB:L77117 PID:1591789 percent identity: 34.85; identified by sequence similarity; putative.
   
 
 0.667
tpiA
Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.658
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.