Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2046Cytochrome oxidase, subunit I, putative; Similar to GP:1773053 percent identity: 25.14; identified by sequence similarity; putative. (248 aa)    
Predicted Functional Partners:
asd-2
Phosphatidylserine decarboxylase (psd2); Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer).
    
 0.981
AF_2044
CDP-diacylglycerol--serine O-phosphatidyltransferase (pssA); Similar to GB:L77117 SP:Q58609 PID:1591841 percent identity: 36.65; identified by sequence similarity; putative.
     
 0.909
AF_2043
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57851 PID:1591114 percent identity: 31.71; identified by sequence similarity; putative.
       0.809
AF_1245
Na+/H+ antiporter (napA-2); Similar to SP:P26235 PID:148316 percent identity: 28.41; identified by sequence similarity; putative.
   
    0.778
AF_2047
Thymidylate synthase, putative; Similar to GB:M19653 SP:P00469 PID:149601 percent identity: 33.14; identified by sequence similarity; putative.
       0.693
tfs
Transcription-associated protein TFIIS; Induces RNA cleavage activity in the RNA polymerase. In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA. The truncated RNAs are able to continue elongation. Involved in transcriptional proofreading and fidelity. Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end. TFS is able to ind [...]
       0.624
AF_1234
Mutator protein MutT (mutT); Similar to GB:L77117 PID:1500003 percent identity: 63.64; identified by sequence similarity; putative.
       0.616
AF_2048
Predicted coding region AF_2048; Hypothetical protein; identified by GeneMark; putative.
       0.517
AF_2049
Conserved hypothetical protein; Similar to GB:L77117 PID:1591954 percent identity: 31.36; identified by sequence similarity; putative.
       0.517
AF_2050
Conserved hypothetical protein; Similar to GB:L77117 PID:1591729 percent identity: 42.74; identified by sequence similarity; putative; Belongs to the UPF0047 family.
       0.517
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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