Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2049Conserved hypothetical protein; Similar to GB:L77117 PID:1591954 percent identity: 31.36; identified by sequence similarity; putative. (378 aa)    
Predicted Functional Partners:
AF_2361
mRNA 3'-end processing factor, putative; Similar to GP:1707412 percent identity: 30.49; identified by sequence similarity; putative.
  
 0.926
AF_0532
mRNA 3'-end processing factor, putative; Similar to GB:L77117 SP:Q60355 PID:1590845 percent identity: 39.36; identified by sequence similarity; putative.
   
 0.905
endA
tRNA intron endonuclease (endA); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
    
 0.876
AF_2048
Predicted coding region AF_2048; Hypothetical protein; identified by GeneMark; putative.
       0.807
AF_2050
Conserved hypothetical protein; Similar to GB:L77117 PID:1591729 percent identity: 42.74; identified by sequence similarity; putative; Belongs to the UPF0047 family.
       0.803
rlmE
Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
       0.787
rpl40e
LSU ribosomal protein L40E (rpl40E); Similar to GB:L77117 SP:P54058 PID:1591423 percent identity: 73.33; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
     
  0.744
AF_2047
Thymidylate synthase, putative; Similar to GB:M19653 SP:P00469 PID:149601 percent identity: 33.14; identified by sequence similarity; putative.
 
     0.639
AF_2333
Conserved hypothetical protein; Similar to GB:L77117 PID:1591952 percent identity: 45.50; identified by sequence similarity; putative.
 
     0.623
AF_1822
Serine/threonine phosphatase (ppa); Similar to PID:1016001 percent identity: 31.94; identified by sequence similarity; putative.
  
  
  0.618
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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