node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AF_2068 | cofC | AF_2068 | AF_2061 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.767 |
AF_2068 | eif6 | AF_2068 | AF_2065 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. | 0.923 |
AF_2068 | ftsY | AF_2068 | AF_2062 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | Signal recognition particle receptor (dpa); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.843 |
AF_2068 | pfdA | AF_2068 | AF_2063 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | C-myc binding protein, putative; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity). | 0.942 |
AF_2068 | rfcS | AF_2068 | AF_2060 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | Activator 1, replication factor C, 35 KD subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA. Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.749 |
AF_2068 | rpl18a | AF_2068 | AF_2064 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | LSU ribosomal protein LXA (rplXA); Similar to SP:P14125 percent identity: 53.85; identified by sequence similarity; putative. | 0.889 |
AF_2068 | rps19e | AF_2068 | AF_2069 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | SSU ribosomal protein S19E (rps19E); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. | 0.973 |
AF_2068 | taw1 | AF_2068 | AF_2261 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | 0.527 |
AF_2068 | taw3 | AF_2068 | AF_2059 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.788 |
cofC | AF_2068 | AF_2061 | AF_2068 | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | 0.767 |
cofC | eif6 | AF_2061 | AF_2065 | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. | 0.773 |
cofC | ftsY | AF_2061 | AF_2062 | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | Signal recognition particle receptor (dpa); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.773 |
cofC | pfdA | AF_2061 | AF_2063 | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | C-myc binding protein, putative; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity). | 0.773 |
cofC | rfcS | AF_2061 | AF_2060 | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | Activator 1, replication factor C, 35 KD subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA. Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.746 |
cofC | rpl18a | AF_2061 | AF_2064 | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | LSU ribosomal protein LXA (rplXA); Similar to SP:P14125 percent identity: 53.85; identified by sequence similarity; putative. | 0.773 |
cofC | rps19e | AF_2061 | AF_2069 | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | SSU ribosomal protein S19E (rps19E); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. | 0.767 |
cofC | taw3 | AF_2061 | AF_2059 | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.746 |
eif6 | AF_2068 | AF_2065 | AF_2068 | Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family. | 0.923 |
eif6 | cofC | AF_2065 | AF_2061 | Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.773 |
eif6 | ftsY | AF_2065 | AF_2062 | Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. | Signal recognition particle receptor (dpa); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.847 |