node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AF_0382 | AF_0517 | AF_0382 | AF_0517 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | 0.907 |
AF_0382 | AF_0780 | AF_0382 | AF_0780 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | Predicted coding region AF_0780; Hypothetical protein; identified by GeneMark; putative. | 0.909 |
AF_0382 | fen | AF_0382 | AF_0264 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | 0.724 |
AF_0382 | lig | AF_0382 | AF_0623 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | DNA ligase (lig); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.571 |
AF_0382 | pcn | AF_0382 | AF_0335 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.935 |
AF_0382 | pol | AF_0382 | AF_0497 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | DNA polymerase B1 (polB); Similar to PID:807830 percent identity: 45.13; identified by sequence similarity; putative. | 0.835 |
AF_0382 | priL | AF_0382 | AF_0336 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | Conserved hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.752 |
AF_0382 | priS | AF_0382 | AF_0742 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | DNA primase, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May [...] | 0.653 |
AF_0382 | rfcS | AF_0382 | AF_2060 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | Activator 1, replication factor C, 35 KD subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA. Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.840 |
AF_0517 | AF_0382 | AF_0517 | AF_0382 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | 0.907 |
AF_0517 | AF_0780 | AF_0517 | AF_0780 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | Predicted coding region AF_0780; Hypothetical protein; identified by GeneMark; putative. | 0.923 |
AF_0517 | eif6 | AF_0517 | AF_2065 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. | 0.479 |
AF_0517 | fen | AF_0517 | AF_0264 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | 0.861 |
AF_0517 | lig | AF_0517 | AF_0623 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | DNA ligase (lig); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.567 |
AF_0517 | pcn | AF_0517 | AF_0335 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.886 |
AF_0517 | pol | AF_0517 | AF_0497 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | DNA polymerase B1 (polB); Similar to PID:807830 percent identity: 45.13; identified by sequence similarity; putative. | 0.971 |
AF_0517 | priL | AF_0517 | AF_0336 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | Conserved hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.927 |
AF_0517 | priS | AF_0517 | AF_0742 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | DNA primase, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May [...] | 0.815 |
AF_0517 | rfcS | AF_0517 | AF_2060 | Cell division control protein 21 (cdc21); Similar to GB:L77117 SP:Q57809 PID:1591071 percent identity: 32.75; identified by sequence similarity; putative; Belongs to the MCM family. | Activator 1, replication factor C, 35 KD subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA. Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.985 |
AF_0780 | AF_0382 | AF_0780 | AF_0382 | Predicted coding region AF_0780; Hypothetical protein; identified by GeneMark; putative. | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | 0.909 |