Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ftsYSignal recognition particle receptor (dpa); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (340 aa)    
Predicted Functional Partners:
srp54
Signal recognition particle, subunit SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (Probable). Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
0.997
srp19
Signal recognition particle, subunit SRP19 (srp19); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
   
 
 0.982
secY
Protein translocase, subunit SEC61 alpha (secY); The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 
 0.965
eif6
Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
     
 0.911
rpl18a
LSU ribosomal protein LXA (rplXA); Similar to SP:P14125 percent identity: 53.85; identified by sequence similarity; putative.
  
    0.909
rpl39e
LSU ribosomal protein L39E (rpl39E); Similar to GB:L77117 SP:P54056 PID:1591404 percent identity: 56.86; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL39 family.
     
 0.909
pfdA
C-myc binding protein, putative; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
       0.906
rpl31e
LSU ribosomal protein L31E (rpl31E); Similar to GB:L77117 SP:P54009 PID:1590847 percent identity: 50.62; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL31 family.
       0.906
AF_2068
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family.
       0.904
rps19e
SSU ribosomal protein S19E (rps19E); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
     
 0.904
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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