Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
eif6Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (215 aa)    
Predicted Functional Partners:
rpl31e
LSU ribosomal protein L31E (rpl31E); Similar to GB:L77117 SP:P54009 PID:1590847 percent identity: 50.62; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL31 family.
 
 
 0.998
rpl18a
LSU ribosomal protein LXA (rplXA); Similar to SP:P14125 percent identity: 53.85; identified by sequence similarity; putative.
  
 
 0.997
rps19e
SSU ribosomal protein S19E (rps19E); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
 
 
 0.989
rpl3
LSU ribosomal protein L3P (rpl3P); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 0.981
rpl11
LSU ribosomal protein L11P (rpl11P); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
 
 0.980
rpl30e
LSU ribosomal protein L30E (rpl30E); Similar to GB:L77117 SP:P54061 PID:1591698 percent identity: 41.67; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL30 family.
  
 
 0.979
rpl7ae
LSU ribosomal protein L7AE (rpl7AE); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 
 0.970
rpl10
LSU ribosomal protein L10E (rpl10E); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
 
 
 0.968
rpl1
LSU ribosomal protein L1P (rpl1P); Binds directly to 23S rRNA. Probably involved in E site tRNA release.
  
 
 0.964
fusA
Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...]
   
 
 0.959
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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