Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_2070Conserved hypothetical protein; Similar to SP:P54454 PID:1303790 GB:AL009126 percent identity: 33.90; identified by sequence similarity; putative. (75 aa)    
Predicted Functional Partners:
AF_2068
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family.
       0.906
rps19e
SSU ribosomal protein S19E (rps19E); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
       0.906
rpl31e
LSU ribosomal protein L31E (rpl31E); Similar to GB:L77117 SP:P54009 PID:1590847 percent identity: 50.62; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL31 family.
       0.903
rpl39e
LSU ribosomal protein L39E (rpl39E); Similar to GB:L77117 SP:P54056 PID:1591404 percent identity: 56.86; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL39 family.
       0.903
eif6
Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
       0.902
rpl18a
LSU ribosomal protein LXA (rplXA); Similar to SP:P14125 percent identity: 53.85; identified by sequence similarity; putative.
       0.895
pfdA
C-myc binding protein, putative; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
       0.892
ftsY
Signal recognition particle receptor (dpa); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
     
 0.884
rpl11
LSU ribosomal protein L11P (rpl11P); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
   0.798
cofC
Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
       0.767
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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