Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_2073Formylmethanofuran:tetrahydromethanopterin formyltransferase (ftr-1); Similar to GB:X70784 PID:452327 SP:Q49168 percent identity: 45.97; identified by sequence similarity; putative; Belongs to the FTR family. (301 aa)    
Predicted Functional Partners:
AF_1930
Tungsten formylmethanofuran dehydrogenase, subunit A (fwdA); Similar to GB:L77117 PID:1591795 percent identity: 48.91; identified by sequence similarity; putative.
 
 
 0.994
AF_1929
Tungsten formylmethanofuran dehydrogenase, subunit B (fwdB-2); Similar to GP:1781026 percent identity: 49.40; identified by sequence similarity; putative.
 
 
 0.990
mch
N5,N10-methenyltetrahydromethanopterin cyclohydrolase (mch); Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
 
 0.990
AF_1650
Tungsten formylmethanofuran dehydrogenase, subunit B (fwdB-1); Similar to PID:871464 GB:AE000666 PID:1890212 percent identity: 34.99; identified by sequence similarity; putative.
 
 
 0.989
fae-hps
D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hps-2); Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
  
  
 0.980
AF_1931
Tungsten formylmethanofuran dehydrogenase, subunit C (fwdC); Similar to GB:L77117 PID:1591797 percent identity: 44.09; identified by sequence similarity; putative.
 
  
 0.975
AF_1928
Tungsten formylmethanofuran dehydrogenase, subunit D (fwdD-2); Similar to GB:L77117 PID:1591794 percent identity: 52.59; identified by sequence similarity; putative.
 
  
 0.969
cdhE
acetyl-CoA decarbonylase/synthase, subunit gamma (cdhE); Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
     
 0.945
cdhC
acetyl-CoA decarbonylase/synthase, subunit beta (cdhC); Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
     
 0.945
AF_1644
Tungsten formylmethanofuran dehydrogenase, subunit F (fwdF); Similar to GB:L77117 PID:1591792 percent identity: 38.21; identified by sequence similarity; putative.
    
 0.925
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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