Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2080Predicted coding region AF_2080; Hypothetical protein; identified by GeneMark; putative. (177 aa)    
Predicted Functional Partners:
AF_2077
Predicted coding region AF_2077; Hypothetical protein; identified by GeneMark; putative.
       0.866
AF_2079
Predicted coding region AF_2079; Hypothetical protein; identified by GeneMark; putative.
      
0.824
AF_2081
Predicted coding region AF_2081; Hypothetical protein; identified by GeneMark; putative.
      
0.811
AF_2078
Predicted coding region AF_2078; Hypothetical protein; identified by GeneMark; putative.
       0.749
AF_2076
Predicted coding region AF_2076; Hypothetical protein; identified by GeneMark; putative.
       0.689
thiE
Thiamine phosphate pyrophosphorylase (thiE); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.516
thiM
Hydroxyethylthiazole kinase (thiM); Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
       0.516
AF_2082
Predicted coding region AF_2082; Hypothetical protein; identified by GeneMark; putative.
       0.513
AF_2073
Formylmethanofuran:tetrahydromethanopterin formyltransferase (ftr-1); Similar to GB:X70784 PID:452327 SP:Q49168 percent identity: 45.97; identified by sequence similarity; putative; Belongs to the FTR family.
       0.425
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (10%) [HD]