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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2085Oxaloacetate decarboxylase, biotin carboxyl carrier subunit, putative; Similar to GB:M80523 SP:P29337 PID:153584 percent identity: 38.74; identified by sequence similarity; putative. (142 aa)    
Predicted Functional Partners:
AF_2084
Oxaloacetate decarboxylase, sodium ion pump subunit (oadB); Similar to GB:M96434 SP:Q03031 PID:154198 percent identity: 59.83; identified by sequence similarity; putative.
  
 
 0.992
pycA
Biotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.944
AF_0435
enoyl-CoA hydratase (fad-1); Similar to PID:755067 percent identity: 47.64; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
    
 0.917
AF_2216
methylmalonyl-CoA decarboxylase, biotin carboxyl carrier subunit (mmdC); Similar to GB:L22208 GB:Z24754 PID:415596 PID:415918 percent identity: 36.22; identified by sequence similarity; putative.
  
  
 
0.908
AF_0991
glutaryl-CoA dehydrogenase (gcdH); Similar to GB:U69141 SP:Q92947 PID:1549327 PID:1905909 PID:2316112 percent identity: 48.68; identified by sequence similarity; putative.
    
 0.907
AF_0333
4-hydroxyphenylacetate-3-hydroxylase (hpaA-1); Similar to PID:974146 percent identity: 22.35; identified by sequence similarity; putative.
     
  0.900
AF_0074
Biotin operon repressor/biotin--[acetyl CoA carboxylase] ligase (birA); Similar to SP:P42975 PID:1146239 PID:755608 PID:773349 GB:AL009126 percent identity: 36.59; identified by sequence similarity; putative.
 
 
 
 0.847
AF_2086
Protease inhibitor, putative; Similar to GB:A16760 GB:A17005 PID:489958 PID:512422 PID:512424 percent identity: 37.04; identified by sequence similarity; putative.
       0.773
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
   
   0.758
AF_2088
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative.
       0.642
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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