Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AF_2089Conserved hypothetical protein; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (313 aa)    
Predicted Functional Partners:
AF_1396
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58217 PID:1591499 percent identity: 44.68; identified by sequence similarity; putative.
     0.923
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
       0.906
AF_2088
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative.
       0.906
mch
N5,N10-methenyltetrahydromethanopterin cyclohydrolase (mch); Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
   
 0.769
AF_2073
Formylmethanofuran:tetrahydromethanopterin formyltransferase (ftr-1); Similar to GB:X70784 PID:452327 SP:Q49168 percent identity: 45.97; identified by sequence similarity; putative; Belongs to the FTR family.
 
     0.765
AF_1414
Dihydropteroate synthase; Similar to GB:L77117 SP:Q57571 PID:1590884 percent identity: 40.82; identified by sequence similarity; putative.
 
     0.755
AF_1930
Tungsten formylmethanofuran dehydrogenase, subunit A (fwdA); Similar to GB:L77117 PID:1591795 percent identity: 48.91; identified by sequence similarity; putative.
 
     0.749
AF_2257
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58186 PID:1499596 percent identity: 30.64; identified by sequence similarity; putative.
 
     0.748
AF_1835
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57680 PID:1499004 percent identity: 33.08; identified by sequence similarity; putative.
 
     0.747
AF_0713
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (hisA-1); Similar to GB:L77117 SP:Q58114 PID:1591418 percent identity: 37.50; identified by sequence similarity; putative; Belongs to the HisA/HisF family.
 
     0.731
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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