Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2097Conserved hypothetical protein; Similar to GB:L77117 PID:1592033 percent identity: 34.93; identified by sequence similarity; putative; Belongs to the LarC family. (395 aa)    
Predicted Functional Partners:
AF_1275
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57629 PID:1498937 percent identity: 51.82; identified by sequence similarity; putative.
 
  
 0.955
AF_1556
Conserved hypothetical protein; Similar to PID:1652988 percent identity: 38.22; identified by sequence similarity; putative.
  
 0.947
AF_0559
Conserved hypothetical protein; Similar to PID:1652988 percent identity: 38.22; identified by sequence similarity; putative.
  
 0.942
radB
DNA repair protein REC; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity).
       0.906
AF_0049
Predicted coding region AF_0049; Hypothetical protein; identified by GeneMark; putative.
 
  
 0.761
AF_2098
Cell division control protein 48, AAA family (cdc48-2); Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 61.98; identified by sequence similarity; putative.
       0.596
AF_1843
Cobalamin biosynthesis protein (cbiM-2); May be involved in nickel transport; Belongs to the CbiM family. NikM subfamily.
 
    0.574
AF_1153
Iron-sulfur cluster binding protein; Similar to PID:1652823 percent identity: 27.94; identified by sequence similarity; putative.
 
    0.572
AF_0751
Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
       0.564
queC
Succinoglycan biosynthesis regulator (exsB); Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
       0.555
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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