STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2103Conserved hypothetical protein; Similar to GP:1789136 percent identity: 27.42; identified by sequence similarity; putative. (147 aa)    
Predicted Functional Partners:
AF_2102
Conserved hypothetical protein; Similar to GP:467333 percent identity: 22.22; identified by sequence similarity; putative.
     0.985
AF_2104
Predicted coding region AF_2104; Hypothetical protein; identified by GeneMark; putative.
  
    0.780
AF_2105
Predicted coding region AF_2105; Hypothetical protein; identified by GeneMark; putative.
       0.773
ribB
GTP cyclohydrolase II (ribA-2); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
     
 0.590
ribK
Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
       0.563
AF_2108
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58167 PID:1591468 percent identity: 41.88; identified by sequence similarity; putative.
       0.444
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 
 0.413
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.