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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2109Signal-transducing histidine kinase; Similar to GB:M29450 SP:P16497 GB:M31067 PID:143333 PID:143631 percent identity: 26.96; identified by sequence similarity; putative. (608 aa)    
Predicted Functional Partners:
AF_2419
Response regulator; Similar to PID:1086465 percent identity: 37.93; identified by sequence similarity; putative.
 
 
 
 0.787
AF_1898
Response regulator; Similar to PID:940149 percent identity: 48.70; identified by sequence similarity; putative.
 
 
 
 0.769
AF_1256
Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative.
 
 
 
 0.758
AF_1384
Response regulator; Similar to PID:940149 percent identity: 44.74; identified by sequence similarity; putative.
 
 
 
 0.752
AF_0449
Response regulator; Similar to GB:M59781 SP:P24072 PID:142682 GB:AL009126 percent identity: 38.14; identified by sequence similarity; putative.
 
 
 
 0.750
AF_2249
Response regulator; Similar to PID:940149 percent identity: 44.83; identified by sequence similarity; putative.
 
 
 
 0.742
AF_1473
Response regulator; Similar to PID:1086465 percent identity: 38.64; identified by sequence similarity; putative.
 
 
 
 0.729
AF_1063
Response regulator; Similar to PID:940149 percent identity: 36.28; identified by sequence similarity; putative.
 
 
 
 0.691
AF_2110
Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
     
 0.578
AF_1042
Chemotaxis response regulator (cheY); Similar to PID:940149 percent identity: 62.93; identified by sequence similarity; putative.
 
 
 
 0.571
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.