STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2127Transcriptional regulatory protein, LysR family; Similar to GB:L77117 SP:Q57748 PID:1591023 percent identity: 30.80; identified by sequence similarity; putative. (324 aa)    
Predicted Functional Partners:
rpoD
DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.825
rpoK
DNA-directed RNA polymerase, subunit K (rpoK); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
   
 
 0.796
AF_1886
DNA-directed RNA polymerase, subunit B'' (rpoB2); Similar to SP:P15352 PID:43540 percent identity: 57.14; identified by sequence similarity; putative; Belongs to the RNA polymerase beta chain family.
    
 
 0.747
rpoB1
DNA-directed RNA polymerase, subunit B' (rpoB1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.
    
 
 0.747
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.728
AF_1888
DNA-directed RNA polymerase, subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.706
rpoA2
DNA-directed RNA polymerase, subunit A'' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.706
AF_2129
Aspartate aminotransferase (aspB-2); Similar to PID:1146246 SP:P53001 GB:AL009126 percent identity: 45.38; identified by sequence similarity; putative.
  
  
 0.601
ribH
Riboflavin synthase, subunit beta (ribE); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
     
 0.598
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
  
  
 0.560
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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