Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AF_2129Aspartate aminotransferase (aspB-2); Similar to PID:1146246 SP:P53001 GB:AL009126 percent identity: 45.38; identified by sequence similarity; putative. (379 aa)    
Predicted Functional Partners:
mdh
L-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.
  
 0.962
AF_0227
Chorismate mutase/prephenate dehydratase (pheA); Similar to GB:L42023 SP:P43900 PID:1006481 PID:1221267 PID:1205390 percent identity: 32.15; identified by sequence similarity; putative.
   
 0.939
katG
Peroxidase / catalase (perA); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity.
  
 
 0.938
argG
Argininosuccinate synthetase (argG); Similar to GB:L77117 SP:Q60174 PID:1591132 percent identity: 62.02; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.927
purA
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.919
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
  
 0.919
mfnA
Group II decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily.
  
 
 0.917
argJ
Glutamate N-acetyltransferase (argJ); Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
    
 0.916
AF_1439
Asparagine synthetase (asnB); Similar to GB:L77117 SP:Q58516 PID:1591755 percent identity: 36.88; identified by sequence similarity; putative.
  
 
 0.916
AF_2366
Aspartate aminotransferase (aspB-1); Similar to GB:L77117 SP:Q60317 PID:1592252 percent identity: 42.31; identified by sequence similarity; putative.
  
  
 
0.910
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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