Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2149Conserved hypothetical protein; Similar to GB:L77117 SP:Q58046 PID:1591340 percent identity: 30.14; identified by sequence similarity; putative; Belongs to the UPF0111 family. (211 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
       0.773
AF_0791
Phosphate permease, putative; Similar to GB:L77117 SP:Q58047 PID:1591341 percent identity: 31.10; identified by sequence similarity; putative.
  
  
 0.651
AF_1798
Phosphate permease, putative; Potential transporter for phosphate; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
  
  
 0.651
AF_2369
Predicted coding region AF_2369; Hypothetical protein; identified by GeneMark; putative.
     
 0.650
AF_1801
Conserved hypothetical protein; Similar to GB:L77117 PID:1592115 percent identity: 35.16; identified by sequence similarity; putative.
       0.624
ogt
methylated-DNA-protein-cysteine methyltransferase (ogt); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.624
AF_1695
Thiamine biosynthesis protein (apbA); Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
       0.616
AF_1099
Fumarase (fum-2); Similar to GB:L77117 SP:Q58690 PID:1591932 percent identity: 53.38; identified by sequence similarity; putative.
       0.601
AF_1098
Fumarase (fum-1); Similar to GB:L77117 SP:Q58034 PID:1591328 percent identity: 49.13; identified by sequence similarity; putative.
       0.581
AF_2151
Isochorismatase (entB); Similar to PID:1045016 SP:Q51790 percent identity: 31.21; identified by sequence similarity; putative.
       0.565
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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