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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2155Conserved hypothetical protein; Similar to SP:P54548 PID:1303962 GB:AL009126 percent identity: 33.33; identified by sequence similarity; putative. (234 aa)    
Predicted Functional Partners:
cca
tRNA nucleotidyltransferase (cca); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
     
 0.806
AF_2157
Conserved hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
       0.792
AF_2158
Predicted coding region AF_2158; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_2159
Predicted coding region AF_2159; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_2160
Predicted coding region AF_2160; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_2154
Conserved hypothetical protein; Similar to GB:L77117 PID:1500525 percent identity: 40.14; identified by sequence similarity; putative; Belongs to the UPF0179 family.
       0.748
AF_2161
Predicted coding region AF_2161; Hypothetical protein; identified by GeneMark; putative.
       0.693
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
    0.585
AF_2162
Predicted coding region AF_2162; Hypothetical protein; identified by GeneMark; putative.
       0.501
AF_2163
Predicted coding region AF_2163; Hypothetical protein; identified by GeneMark; putative.
       0.501
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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