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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccatRNA nucleotidyltransferase (cca); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (437 aa)    
Predicted Functional Partners:
endA
tRNA intron endonuclease (endA); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
 
   
 0.927
AF_2157
Conserved hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
     0.878
AF_2155
Conserved hypothetical protein; Similar to SP:P54548 PID:1303962 GB:AL009126 percent identity: 33.33; identified by sequence similarity; putative.
     
 0.806
AF_2154
Conserved hypothetical protein; Similar to GB:L77117 PID:1500525 percent identity: 40.14; identified by sequence similarity; putative; Belongs to the UPF0179 family.
 
     0.801
AF_0531
Molybdenum cofactor biosynthesis protein (moeB); Similar to PID:1653525 percent identity: 43.96; identified by sequence similarity; putative.
  
 
 0.791
AF_0553
Thiamine biosynthesis protein (thiF); Similar to SP:P30138 PID:396331 PID:414234 GB:U00096 PID:1790425 percent identity: 38.75; identified by sequence similarity; putative.
  
 
 0.791
AF_1441
Predicted coding region AF_1441; Hypothetical protein; identified by GeneMark; putative.
  
 
 0.791
AF_2158
Predicted coding region AF_2158; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_2159
Predicted coding region AF_2159; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_2160
Predicted coding region AF_2160; Hypothetical protein; identified by GeneMark; putative.
       0.773
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.