Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_21732-nitropropane dioxygenase (ncd2); Similar to GP:726338 percent identity: 39.70; identified by sequence similarity; putative. (274 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase (ilvC); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH or NADH to yield (R)-2,3-dihydroxy-isovalerate. It is able to use both NADPH and NADH, but has a preference for NADH.
    
 0.671
AF_1207
2-deoxy-D-gluconate 3-dehydrogenase (kduD); Similar to SP:Q05528 GB:X62073 PID:48986 percent identity: 45.31; identified by sequence similarity; putative.
 
  
 0.643
AF_0033
Acyl carrier protein synthase (acaA-1); Similar to PID:1197357 percent identity: 28.62; identified by sequence similarity; putative.
  
  
 0.554
AF_2415
Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family.
  
  
 0.554
pycA
Biotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
  
 0.541
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
     
 0.507
rpl29
LSU ribosomal protein L29P (rpl29P); Similar to SP:P10971 GB:J05222 PID:148808 percent identity: 44.62; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uL29 family.
  
    0.437
AF_0435
enoyl-CoA hydratase (fad-1); Similar to PID:755067 percent identity: 47.64; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.419
AF_0685
enoyl-CoA hydratase (fad-2); Similar to PID:755067 percent identity: 39.92; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.419
AF_0963
enoyl-CoA hydratase (fad-3); Similar to PID:755067 percent identity: 48.56; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.419
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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