Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
AF_2187Predicted coding region AF_2187; Hypothetical protein; identified by GeneMark; putative. (98 aa)    
Predicted Functional Partners:
AF_2184
Conserved hypothetical protein; Similar to PID:1653500 percent identity: 33.33; identified by sequence similarity; putative.
       0.584
sucD2
succinyl-CoA synthetase, alpha subunit (sucD-2); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.584
sucC2
succinyl-CoA synthetase, beta subunit (sucC-2); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.584
AF_2183
Predicted coding region AF_2183; Hypothetical protein; identified by GeneMark; putative.
       0.524
AF_2188
Conserved hypothetical protein; Similar to PID:2347170 percent identity: 30.67; identified by sequence similarity; putative.
       0.510
AF_2182
Conserved hypothetical protein; Similar to GP:1707766 percent identity: 39.76; identified by sequence similarity; putative.
       0.433
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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