| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AF_0428 | dys1 | AF_0428 | AF_2195 | GTP-binding protein, GTP1/OBG-family; Similar to GB:L77117 PID:1592057 percent identity: 43.92; identified by sequence similarity; putative. | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.521 |
| AF_0428 | flpA | AF_0428 | AF_2087 | GTP-binding protein, GTP1/OBG-family; Similar to GB:L77117 PID:1592057 percent identity: 43.92; identified by sequence similarity; putative. | Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.897 |
| AF_0428 | rpl6 | AF_0428 | AF_1909 | GTP-binding protein, GTP1/OBG-family; Similar to GB:L77117 PID:1592057 percent identity: 43.92; identified by sequence similarity; putative. | LSU ribosomal protein L6P (rpl6P); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.852 |
| AF_0646 | dys1 | AF_0646 | AF_2195 | Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family. | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.446 |
| AF_0646 | eif5a | AF_0646 | AF_0645 | Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family. | Translation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.946 |
| AF_2194 | dys1 | AF_2194 | AF_2195 | rRNA (adenine-N6)-methyltransferase, putative; Similar to GB:M74717 PID:153346 percent identity: 29.17; identified by sequence similarity; putative. | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.663 |
| AF_2194 | flpA | AF_2194 | AF_2087 | rRNA (adenine-N6)-methyltransferase, putative; Similar to GB:M74717 PID:153346 percent identity: 29.17; identified by sequence similarity; putative. | Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.603 |
| AF_2194 | mfnB | AF_2194 | AF_2196 | rRNA (adenine-N6)-methyltransferase, putative; Similar to GB:M74717 PID:153346 percent identity: 29.17; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). | 0.466 |
| dys1 | AF_0428 | AF_2195 | AF_0428 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | GTP-binding protein, GTP1/OBG-family; Similar to GB:L77117 PID:1592057 percent identity: 43.92; identified by sequence similarity; putative. | 0.521 |
| dys1 | AF_0646 | AF_2195 | AF_0646 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family. | 0.446 |
| dys1 | AF_2194 | AF_2195 | AF_2194 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | rRNA (adenine-N6)-methyltransferase, putative; Similar to GB:M74717 PID:153346 percent identity: 29.17; identified by sequence similarity; putative. | 0.663 |
| dys1 | eif5a | AF_2195 | AF_0645 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Translation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.944 |
| dys1 | flpA | AF_2195 | AF_2087 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.519 |
| dys1 | mfnB | AF_2195 | AF_2196 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Conserved hypothetical protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). | 0.554 |
| dys1 | rpl6 | AF_2195 | AF_1909 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | LSU ribosomal protein L6P (rpl6P); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.722 |
| dys1 | rtcB | AF_2195 | AF_0862 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Conserved hypothetical protein; GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends; Belongs to the RtcB family. | 0.618 |
| dys1 | tiaS | AF_2195 | AF_2259 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Conserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.501 |
| dys1 | top6A | AF_2195 | AF_0940 | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | DNA topoisomerase VI, subunit A (top6A); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.520 |
| eif5a | AF_0646 | AF_0645 | AF_0646 | Translation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family. | 0.946 |
| eif5a | dys1 | AF_0645 | AF_2195 | Translation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | Deoxyhypusine synthase (dys1-1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.944 |
