Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mfnBConserved hypothetical protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (235 aa)    
Predicted Functional Partners:
AF_0713
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (hisA-1); Similar to GB:L77117 SP:Q58114 PID:1591418 percent identity: 37.50; identified by sequence similarity; putative; Belongs to the HisA/HisF family.
 
   
 0.883
AF_0572
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57900 PID:1499252 percent identity: 34.36; identified by sequence similarity; putative.
 
   
 0.806
AF_0479
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58250 PID:1591527 percent identity: 41.38; identified by sequence similarity; putative.
 
   
 0.787
AF_1930
Tungsten formylmethanofuran dehydrogenase, subunit A (fwdA); Similar to GB:L77117 PID:1591795 percent identity: 48.91; identified by sequence similarity; putative.
 
   
 0.787
AF_1061
Conserved hypothetical protein; Similar to GB:L77117 PID:1591504 percent identity: 42.64; identified by sequence similarity; putative.
 
   
 0.764
AF_1414
Dihydropteroate synthase; Similar to GB:L77117 SP:Q57571 PID:1590884 percent identity: 40.82; identified by sequence similarity; putative.
 
     0.756
AF_1835
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57680 PID:1499004 percent identity: 33.08; identified by sequence similarity; putative.
 
     0.749
mch
N5,N10-methenyltetrahydromethanopterin cyclohydrolase (mch); Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
     0.744
AF_1650
Tungsten formylmethanofuran dehydrogenase, subunit B (fwdB-1); Similar to PID:871464 GB:AE000666 PID:1890212 percent identity: 34.99; identified by sequence similarity; putative.
 
   
 0.740
AF_1518
DNA/pantothenate metabolism flavoprotein, putative; Similar to GB:L77117 SP:Q58140 PID:1499547 percent identity: 51.40; identified by sequence similarity; putative.
 
     0.723
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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