Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2197Potassium channel, putative; Similar to GB:L77117 SP:Q57604 PID:1498918 percent identity: 24.55; identified by sequence similarity; putative. (395 aa)    
Predicted Functional Partners:
AF_1505
Predicted coding region AF_1505; Hypothetical protein; identified by GeneMark; putative.
 
     0.863
AF_2198
Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative.
 
     0.796
leuC2
3-isopropylmalate dehydratase, large subunit (leuC); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
       0.686
AF_1298
Predicted coding region AF_1298; Hypothetical protein; identified by GeneMark; putative.
  
     0.549
AF_1791
Signal sequence peptidase (sec11); Similar to GB:Z47047 SP:P15367 PID:4433 PID:557828 PID:763367 percent identity: 36.30; identified by sequence similarity; putative.
  
     0.529
AF_1901
Conserved hypothetical transmembrane protein; Similar to GB:L77117 SP:Q57904 PID:1591183 percent identity: 27.49; identified by sequence similarity; putative.
 
     0.527
AF_1530
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60351 PID:1590840 percent identity: 45.28; identified by sequence similarity; putative.
  
     0.511
AF_0779
Predicted coding region AF_0779; Hypothetical protein; identified by GeneMark; putative.
  
     0.498
AF_0780
Predicted coding region AF_0780; Hypothetical protein; identified by GeneMark; putative.
  
     0.495
AF_2200
Mutator protein MutT, putative; Similar to GB:L77117 PID:1500003 percent identity: 41.98; identified by sequence similarity; putative.
       0.494
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.