Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_2202Tryptophan-specific permease, putative; Similar to percent identity: 25.23; identified by sequence similarity; putative. (228 aa)    
Predicted Functional Partners:
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
       0.952
AF_2203
Conserved hypothetical protein; Similar to GB:X69895 SP:P39044 PID:40067 percent identity: 30.00; identified by sequence similarity; putative.
  
  
 0.815
AF_0869
Conserved hypothetical protein; Similar to GP:1402531 percent identity: 48.31; identified by sequence similarity; putative; Belongs to the UPF0145 family.
       0.624
AF_2204
Arylsulfatase regulatory protein, putative; Similar to GB:M87049 SP:P25550 GB:M90498 PID:145390 PID:148199 percent identity: 29.93; identified by sequence similarity; putative.
       0.494
AF_2205
Predicted coding region AF_2205; Hypothetical protein; identified by GeneMark; putative.
       0.421
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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