Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2216methylmalonyl-CoA decarboxylase, biotin carboxyl carrier subunit (mmdC); Similar to GB:L22208 GB:Z24754 PID:415596 PID:415918 percent identity: 36.22; identified by sequence similarity; putative. (140 aa)    
Predicted Functional Partners:
AF_2084
Oxaloacetate decarboxylase, sodium ion pump subunit (oadB); Similar to GB:M96434 SP:Q03031 PID:154198 percent identity: 59.83; identified by sequence similarity; putative.
  
 
 0.966
pycA
Biotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.923
AF_0435
enoyl-CoA hydratase (fad-1); Similar to PID:755067 percent identity: 47.64; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
    
 0.915
AF_0963
enoyl-CoA hydratase (fad-3); Similar to PID:755067 percent identity: 48.56; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
    
 0.915
AF_2085
Oxaloacetate decarboxylase, biotin carboxyl carrier subunit, putative; Similar to GB:M80523 SP:P29337 PID:153584 percent identity: 38.74; identified by sequence similarity; putative.
  
  
 
0.908
AF_0991
glutaryl-CoA dehydrogenase (gcdH); Similar to GB:U69141 SP:Q92947 PID:1549327 PID:1905909 PID:2316112 percent identity: 48.68; identified by sequence similarity; putative.
    
 0.907
AF_0333
4-hydroxyphenylacetate-3-hydroxylase (hpaA-1); Similar to PID:974146 percent identity: 22.35; identified by sequence similarity; putative.
     
  0.900
AF_1027
4-hydroxyphenylacetate-3-hydroxylase (hpaA-3); Similar to PID:974146 percent identity: 21.03; identified by sequence similarity; putative.
     
  0.900
AF_2215
methylmalonyl-CoA mutase, subunit alpha, N-terminus (mcmA1); Similar to SP:P11653 PID:581476 percent identity: 51.18; identified by sequence similarity; putative.
       0.798
AF_2217
methylmalonyl-CoA decarboxylase, subunit alpha (mmdA); Similar to GB:L22208 GB:Z24754 PID:415593 PID:415915 percent identity: 62.52; identified by sequence similarity; putative.
 
  
 0.798
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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