Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_2220Predicted coding region AF_2220; Hypothetical protein; identified by GeneMark; putative. (88 aa)    
Predicted Functional Partners:
prs1
Ribose-phosphate pyrophosphokinase (prsA-1); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.929
prs2
Ribose-phosphate pyrophosphokinase (prsA-2); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.929
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
  
 0.929
AF_0682
Succinate dehydrogenase, iron-sulfur subunit B (sdhB); Similar to GB:X70908 PID:396212 percent identity: 51.27; identified by sequence similarity; putative.
  
 
 0.884
AF_0769
Thioredoxin (trx-2); Similar to GB:L77117 SP:Q57755 PID:1591029 percent identity: 38.46; identified by sequence similarity; putative.
 
 0.856
AF_0515
NADH oxidase, putative; Similar to GB:D21803 PID:464216 percent identity: 25.53; identified by sequence similarity; putative.
  
 0.837
AF_0711
Thioredoxin (trx-1); Similar to SP:P06544 GB:M14736 PID:142118 percent identity: 28.36; identified by sequence similarity; putative.
  
 0.837
AF_1284
Thioredoxin (trx-3); Similar to SP:P00275 percent identity: 52.94; identified by sequence similarity; putative.
  
 0.837
AF_1675
Predicted coding region AF_1675; Hypothetical protein; identified by GeneMark; putative.
  
 0.837
AF_2144
Thioredoxin (trx-4); Similar to SP:P37395 percent identity: 48.94; identified by sequence similarity; putative.
  
 0.837
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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