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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2220Predicted coding region AF_2220; Hypothetical protein; identified by GeneMark; putative. (88 aa)    
Predicted Functional Partners:
AF_0769
Thioredoxin (trx-2); Similar to GB:L77117 SP:Q57755 PID:1591029 percent identity: 38.46; identified by sequence similarity; putative.
 
 0.901
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
  
 0.892
AF_0515
NADH oxidase, putative; Similar to GB:D21803 PID:464216 percent identity: 25.53; identified by sequence similarity; putative.
  
 0.887
AF_0711
Thioredoxin (trx-1); Similar to SP:P06544 GB:M14736 PID:142118 percent identity: 28.36; identified by sequence similarity; putative.
  
 0.887
AF_1284
Thioredoxin (trx-3); Similar to SP:P00275 percent identity: 52.94; identified by sequence similarity; putative.
  
 0.887
AF_1675
Predicted coding region AF_1675; Hypothetical protein; identified by GeneMark; putative.
  
 0.887
AF_2144
Thioredoxin (trx-4); Similar to SP:P37395 percent identity: 48.94; identified by sequence similarity; putative.
  
 0.887
AF_2145
Glutaredoxin (grx-2); Acts to maintain redox homeostasis; functions as a protein disulfide reductase; Belongs to the glutaredoxin family.
  
 0.887
AF_2248
Conserved hypothetical protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.
  
 0.887
prs1
Ribose-phosphate pyrophosphokinase (prsA-1); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.879
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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