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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2226Conserved hypothetical protein; Similar to GB:L77117 SP:Q57864 PID:1591124 percent identity: 47.67; identified by sequence similarity; putative. (352 aa)    
Predicted Functional Partners:
tmcA
Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
 0.932
truB
Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
 
 0.806
trm1
N2,N2-dimethylguanosine tRNA methyltransferase (trm1); Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
    
 
 0.784
nep1
Conserved hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
  
 0.770
AF_0746
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57608 PID:1590906 percent identity: 32.75; identified by sequence similarity; putative.
 
 
 0.728
AF_1064
ABC transporter, ATP-binding protein, putative; Similar to PID:1653298 percent identity: 36.02; identified by sequence similarity; putative.
  
     0.641
AF_1810
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57567 PID:1498868 percent identity: 43.77; identified by sequence similarity; putative.
  
     0.636
AF_0918
Pyruvate formate-lyase activating enzyme (act-2); Similar to GB:L77117 SP:Q58214 PID:1499627 percent identity: 42.65; identified by sequence similarity; putative.
  
     0.631
AF_2225
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2); Similar to GB:L77117 PID:1500558 percent identity: 65.99; identified by sequence similarity; putative; Belongs to the FAH family.
       0.556
AF_2078
Predicted coding region AF_2078; Hypothetical protein; identified by GeneMark; putative.
  
   
 0.545
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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