Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_2227Conserved hypothetical protein; Similar to GB:L77117 SP:Q57623 PID:1590916 percent identity: 29.25; identified by sequence similarity; putative. (322 aa)    
Predicted Functional Partners:
glnA
Glutamine synthetase (glnA); Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Beta-glutamate is a much poorer substrate than alpha-glutamate; Belongs to the glutamine synthetase family.
     
 0.806
AF_0998
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57978 PID:1591264 percent identity: 27.52; identified by sequence similarity; putative.
  
     0.539
pdxT
Imidazoleglycerol-phosphate synthase, subunit H, putative; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
      
 0.521
gap
Glyceraldehyde 3-phosphate dehydrogenase (gap); Similar to SP:P10618 PID:149792 percent identity: 56.59; identified by sequence similarity; putative.
      
 0.512
AF_1928
Tungsten formylmethanofuran dehydrogenase, subunit D (fwdD-2); Similar to GB:L77117 PID:1591794 percent identity: 52.59; identified by sequence similarity; putative.
  
     0.415
AF_2228
Sulfite reductase, desulfoviridin-type subunit gamma (dsvC); Similar to GB:L42023 SP:P45184 PID:1007407 PID:1221507 PID:1205607 percent identity: 41.28; identified by sequence similarity; putative.
       0.401
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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